Caseous Lymphadenitis in Iraqi Sheep and Assessment of Vaccination with Commercial Vaccine

Experimental study included 15 lambs which were divided into 3 groups; each group consisted of 5 lambs. A commercial CaseBac vaccine was used to vaccinate group II, while others groups served as positive and negative controls. All lambs in group II were received two doses of vaccine at four weeks interval. The lambs in groups II and III were challenged S/C with 9 x 10 CFU virulent isolated strain of C. pseudotuberculosis. Humoral and cell mediated immune response were detected during the period of experiments, the temperature, pulse rate and respiration rate were determined weekly. The protection in vaccinated group was 100% against challenge dose, while in the group III one lamb died on fifth day post challenge. Pus was appeared in the rest of lambs at the site of injection.